About this Panel
Nutrients are components of foods that are required by the body for healthy living. Stasis describes a state of equilibrium.
People suffer from fatigue and tiredness for a number of reasons. Sometimes however this lack of energy becomes chronic and it becomes difficult to maintain everyday activities. As deficiencies of vitamin B12, folate (B9), iron and vitamin D are all common causes of fatigue, this panel is designed to help you investigate the cause of low energy levels. You can find out more about each test individually in the table below.
Nutris Vitality is our most comprehensive panel offered directly to customers through Nutris.
Vitamin B12 is responsible for a number of important functions in the body including healthy nerves and red blood cells. The current convention, followed by most GPs, is to use Total B12 as the first-line screen for deficiency.
Active B12 (holotranscobalamin - holoTC) is the biologically active fraction of B12 which is required for intracellular metabolism.
Research suggests that Active B12 may be the earliest marker of vitamin B12 depletion. Moreover, unlike Total B12, Active B12 is believed to be a suitable marker to test during pregnancy.
Elevated levels of methylmalonic acid (MMA) in the blood indicate deficiency of B12 or poor utilisation of vitamin B12 by the body's cells. MMA is considered the most representative marker of metabolic vitamin B12 status.
Folate (Vitamin B9) is naturally present in many foods such as vegetables, fruits and grains. It is needed for the body to produce DNA, which is why it is so critical during pregnancy. Along with vitamin B12, folate is responsible for helping maintain a healthy nervous system.
Homocysteine is an amino acid. An elevated level of homocysteine is often the result of low levels of vitamin B12 and folate. Testing for homocysteine levels can therefore be a useful indicator in further investigating a B12 deficiency. Elevated levels are also considered a risk factor for heart disease, Alzheimer’s disease and cancer.
Ferritin is a protein that stores iron and releases it in a controlled fashion. Iron is used for the production of red blood cells and is required for many other metabolic pathways. About two-thirds of the iron stores in the human body exist in the form of ferritin.
Low ferritin is diagnostic of iron deficiency anaemia. High ferritin levels are associated with liver inflammation.
Vitamin D plays a critical role in regulating calcium and phosphorus levels in the body, which keep bones, teeth and muscles healthy. Additionally, it plays an important role in immune function, many chronic diseases and mental health. Specifically, it has been associated with cancer, cardiovascular disease and rickets in children and osteoporosis in adults.
Vitamin D is most commonly absorbed from exposure to the sun, although it can also be found in foods such as oily fish, red meat, liver and egg yolks. Vitamin D deficiency is common in the winter months when sun exposure is reduced.
Who is this panel for?
Nutris Vitality is for individuals worried about anaemia or suffering from fatigue who would like a more comprehensive health check for common nutrient deficiencies.Vitamin D deficiency is very common in the UK, especially in the winter months, due to lack of exposure to the sun. Age is a factor in vitamin B12, folate, iron deficiency, as well as pernicious anaemia and conditions such as Crohn's disease. Those that restrict their diet, such as vegetarians and vegans, may also be more likely to develop deficiencies.
Symptoms of vitamin B12, folate, and iron deficiency include fatigue, lethargy, breathlessness, feeling faint, headaches, heart palpitations, tinnitus and weight loss. Symptoms of vitamin B12 deficiency may also include pale yellow tinged skin, a sore and red tongue, mouth ulcers, depression and pins and needles.
Further iron deficiency symptoms, though less common, include headaches, tinnitus, an altered sense of taste, feeling itchy, a sore or abnormally smooth tongue, hair loss, difficulty swallowing, ulcers on the corners of your mouth and spoon shaped nails.
If you are suffering from fatigue, worried about anaemia or the symptoms described, this test is for you.
* Turnaround time measured from when blood sample is accepted in to the Viapath laboratory and does not include weekends or bank holidays.
Why should I get this panel?
Vitamin B12 insufficiency/deficiency is common in mixed patient populations. However there is no single marker which can reliably diagnose B12 insufficiency/deficiency.
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How It Works
Choose a test panel
Customers are able to select from our ever-growing range of nutritional laboratory tests without a clinician/physician’s referral.
Have your blood collected
Choose to either have your blood taken at the Blood Test Centre at St Thomas’ Hospital in London, or receive a postal pack and have blood drawn by a qualified professional in a clinic of your choice.
Access your report online
Log in to your secure Viapath Nutris account to access your laboratory report with commentary from a registered healthcare scientist.